Chronic kidney disease (CKD) involves gradual loss of functioning of kidneys. The normal function of kidneys are to filter out and excrete wastes, and excess fluids from the blood are excreted through urine. However, when an individual is suffering from chronic kidney disease, kidneys cannot perform their natural function and wastes, fluids, and electrolytes build up in the body in excess amounts. Signs and symptoms of chronic kidney disease are not apparent until kidney function becomes significantly impaired.
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The global chronic kidney disease drugs market was valued at US$ 12,468.2 million in 2017 and is expected to witness a robust CAGR of 3.1% over the forecast period (2018 – 2026).
The supportive treatment of chronic kidney disease includes delaying the disease progression and kidney damage. Diseases and conditions such as type 1 or type 2 diabetes, high blood pressure, polycystic kidney disease, and recurrent kidney infection leads to chronic kidney disease. Factors that increase risk of chronic kidney disease include diabetes, high blood pressure, smoking, obesity, and others.
Management of the disease involves managing the co-morbidities such as blood pressure, diabetes medications, medications to lower cholesterol levels, and anemia treatment. Kidney dialysis and kidney transplant may become a necessity, as the condition becomes worse. There is no direct medication available for the treatment of chronic kidney disease. Chronic kidney diseases may trigger other healthcare issues such as cardiovascular diseases.
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Amgen Inc., Teva Pharmaceutical Industries Ltd., Pfizer Inc., AstraZeneca Plc, F. Hoffmann-La Roche Ltd., Sanofi S.A., Kissei Pharmaceutical Co. Ltd., AbbVie Inc., GlaxoSmithKline Plc, and Keryx Biopharmaceuticals Inc.
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