The Global Kidney Cancer Drugs Market, by Therapy Class (Targeted Therapy, Immunotherapy and Chemotherapy), by Pharmacological Class (Angiogenesis Inhibitors, mTOR Inhibitors, Cytokines and Others (Immune Checkpoint Inhibitors, CTLA-4 inhibitors, Antimetabolites and Others)), by Distribution Channel (Hospital Pharmacy, Retail Pharmacy, and Online Pharmacy), and by Region (North America, Latin America, Europe, Asia Pacific, Middle East, and Africa) was valued at US$ 4.6 billion in 2018, and is projected to exhibit a CAGR of 6.4% during the forecast period (2018 – 2026), as highlighted in a new report published by Coherent Market Insights.
Various key drug manufacturers are increasingly gaining regulatory drug approval for the treatment of renal cell carcinoma. These key players are launching novel and superior drug candidates in the market to capture more market share. Growing launch of innovative drugs for the treatment of renal cell carcinoma will fuel the growth of market during the forecast period.
For instance, in April 2018, U.S. Food and Drug Administration (FDA) approved Bristol-Myers Squibb Company’s Opdivo (nivolumab) 3 mg/kg plus Yervoy (ipilimumab) 1 mg/kg, injections for intravenous use, as the first immuno-oncology combination therapy for previously untreated patients with intermediate, and poor-risk advanced renal cell carcinoma (RCC). The combination decreased the risk of death by 37 percent compared to Sutent: a kinase inhibitor indicated for the treatment of advanced renal cell carcinoma (RCC) and the adjuvant treatment of adult patients at high risk of recurrent RCC following nephrectomy.
In December 2017, the U.S. FDA granted regular approval to Exelixis, Inc.’s cabozantinib (Cabometyx) as a first line treatment for patients with advanced renal cell carcinoma (RCC). In 2016, FDA approved Cabometyx for treatment of patients with advanced RCC who received prior anti-angiogenic therapy.
Furthermore, key players are focusing on product development through strategic collaborations and commercial expansion in emerging markets. This could lead to make market more competitive, increase revenue growth of key players, and offer lucrative growth outlook during the forecast period.
Biosimilar development is gaining traction as a promising market opportunity in kidney cancer therapeutics. Several biotech companies launched Avastin biosimilars across several cancer indications in emerging markets such as India, Russia, and Argentina. For instance, in November 2017, Biocon Ltd. launched its biosimilar, bevacizumab, for the treatment of several types of cancer, under the brand name Krabeva in India, in 100 mg/4 ml vials and 400 mg/16 ml vials formulation. Krabeva is indicated as a first-line treatment for patients with metastatic colorectal cancer and used to treat lung, kidney, cervical, ovarian, and brain cancers.
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Key Takeaways of the Kidney Cancer Drugs Market:
The global kidney cancer drugs market is expected to exhibit a CAGR of 4% during the forecast period, owing to increasing engagement of key players in gaining drug approval and expand its market presence.
Among therapeutic class, targeted therapy segment accounted for major market share in 2017. Researchers in oncology field are focusing in the kidney cancer cells and developing newer drugs that target molecular and genetic changes. Targeted drugs are different from standard chemotherapy drugs and provide satisfactory result in kidney cancer treatment, where chemotherapy has not been shown to be very effective.
Among pharmacologic class, angiogenesis inhibitors segment accounted for the largest share in 2017. Angiogenesis inhibitor drugs play an important role in restricting the growth of cancer cells. Angiogenesis inhibitors blocks nutrients and oxygen supply to tumor in the kidney. Some of the angiogenesis inhibitors drugs used in kidney cancer treatment include Axitinib (Inlyta), Bevacizumab (Avastin), and Cabozantinib (Cometriq), among others.
Major players operating in the global kidney cancer drugs market include Pfizer Inc., Novartis International AG, Genentech, Inc., Active Biotech AB, Amgen Inc., Bayer AG, Cipla Limited, Hoffmann-La Roche AG, Bristol-Myers Squibb Company, Eisai Co., Ltd. and Exelixis, Inc.
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